Novalis Biotech is an early stage venture capital investor in life sciences

We welcome innovative concepts in healthcare and aim to support their development already at the state of incorporation.

Our investment focus is “enabling technologies” in life sciences. We strongly believe in capital light platform technology and close interaction with customers already early in the life of the company. Focus areas are: innovative research and manufacturing tools, bioinformatics, genomics, diagnostics and digital health.

We focus on early-stage start-ups, from (pre-)seed stage to series A, and support their evolution by providing funding, sharing our professional and academic connections, and help to shape the business strategy in order to create value for all stakeholders.


New start-up Trince raises EUR 4 million for innovative technology to produce personalized cancer therapies safer, cheaper, and faster

New start-up Trince raises EUR 4 million for innovative technology to produce personalized cancer therapies safer, cheaper, and faster

Trince, a spin-off of Ghent University (UGent), is developing innovative and efficient technology to insert genetic material into cells.
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Novalis Biotech Acceleration Modality.AI – technology that ‘self-drives’ neurological and psychiatric assessments

Novalis Biotech Acceleration Modality.AI – technology that ‘self-drives’ neurological and psychiatric assessments

Modality.AI, pioneering AI technology for assessing neurological and psychiatric conditions remotely and in clinical settings through speech and facial measurements, has received a $2.1 million...
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Epigenetics company Epify progresses colorectal cancer program and files first patent application

Epigenetics company Epify progresses colorectal cancer program and files first patent application

    Maastricht, The Netherlands, July 6, 2021 - Epify announces a patent filing in the colorectal cancer (CRC) program. The patent claims multiple epigenetic...
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Novalis Portfolio


Trince is dedicated to advancing cell-based science and therapeutics by facilitating the delivery of molecules into cells, both in vitro and ex vivo. The company’s LumiPore transfection platform, which is covered by a portfolio of pending patents, is used to deliver a wide variety of effector molecules (e.g. nucleic acids or proteins) into virtually any cell type, including hard-to-transfect cells such as immune cells for cell therapies. The technology ensures that this is done in a gentle manner, maximizing the therapeutic quality of the final cell product.


Modality.AI, Inc. (“Modality”) has developed the first multimodal assessment platform to track the progression of neurological and psychiatric diseases through the analysis of facial musculature and phonetic enunciation, using a virtual agent to guide participants through standardized protocols. Modality’s rich, objective, and accurate audiovisual biomarkers expedite the development of therapies for diseases such as Parkinson’s, schizophrenia, depression, and autism, as well as the diagnosis and tracking of treatment efficacy at scale, as used by some of the leading clinical institutions in the world, including UCSF, MGH, NYU, Purdue, and the Charité.

Modality was founded by world-class AI experts with over 200 publications and issued patents and several successful exits. Modality is venture backed and based in San Francisco, CA.


RheaVita has developed a continuous, controlled freeze-drying technology that integrates all the traditional freeze-drying process steps into one continuous production line.

By spinning the glass vials during the freezing process, a thin layer of product coats the inner lining of the vial. Following drying, the final solid freeze-dried product is obtained. Compared to the traditional freeze-drying process, RheaVita’s approach has several advantages, including very fast product and process development with limited experimental efforts, avoiding scale-up issues, reducing cycle times, lower production costs, less clean room space requirements, improving quality assurance and improved and uniform product quality and process uniformity.


Grapheal develops wearable and disposable biosensors enabling continuous monitoring and in-field diagnosis. It empowers caregivers with an improved and individualized assessment tool for precision medicine. See more on


Enzyre, based in Nijmegen, The Netherlands, is a spin-out from Radboud University Medical Center, developing Enzypad, a near patient diagnostic and monitoring device initially focused on blood coagulation. Enzyre’s platform technology is unique as it requires just a small volume of blood and is able to measure up to twelve (12) biomarkers simultaneously without any laboratory infrastructure; at home, on the road or in a critical care setting. Enzyre’s proprietary technology is a small hand-held diagnostic tool using disease specific single use microfluidic cartridges with high sensitivity and specificity. It has broad applicability in several disease areas.


Cergentis is an innovative leader in genomics, provides kits and services based on its proprietary Targeted Locus Amplification (TLA) technology to leading diagnostic labs, research institutes and pharmaceutical companies worldwide. TLA enables rapid, cost-effective and complete next generation sequencing of genes of interest as well as the detection of all single nucleotide and structural variants. Cergentis recently launched TLA for complete cancer gene sequencing, reporting superior data over conventional diagnostic and gene sequencing techniques in FFPE tumour samples.


Fertiga ( is a spin-off from Vrije Universiteit Brussel (VUB) on the basis of research carried out over the past 10 years within the VUB and University hospital of Brussels (UZ Brussels). Our objective is to become a major player in improving fertility treatment outcomes. We improve efficiency of IVF by analysis of gene expressions in cells surrounding the egg cell. Our goal is to reach ‘one child with one try’.


Epigenetic Biomarkers for Cancer Diagnosis and Personalized Treatment

Epify develops epigenetic biomarkers which control gene activity and are implicated in a wide range of cancers, driving and influencing the course of the disease. Using these biomarkers, Epify aims to drive earlier detection and more accurate diagnosis, facilitating personalized oncology and a better prognosis for cancer patients.

See more on wants to break down data silos and transform healthcare with the power of artificial intelligence. End users can collect all their medical information in the app. By agreeing to also share their anonymized data with researchers, they feed the machine learning capacities of the platform, getting more accurate results and accelerating medical research to the benefit of generations to come.
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myNEO identifies and evaluates patient-specific mutant peptides that are present (DNA) and expressed (RNA), but absent in the patient’s germline.
This analysis is the first step in any personalised immunotherapy.